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Boris Pasche Selected Research

Transforming Growth Factor-beta Type I Receptor

1/2014TGFBR1 and cancer susceptibility.
6/2011TGFBR1 signaling and breast cancer.
5/2010Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs.
1/2010Tgf-beta signaling alterations and colon cancer.
12/2009Tgfbr1 haploinsufficiency inhibits the development of murine mutant Kras-induced pancreatic precancer.
9/2009TGFBR1 haplotypes and risk of non-small-cell lung cancer.
1/2009Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.
12/2008Role of polymorphisms in Adamantiades-Behçet's disease.
9/2008Germline allele-specific expression of TGFBR1 confers an increased risk of colorectal cancer.
3/2008TGFBR1*6A enhances the migration and invasion of MCF-7 breast cancer cells through RhoA activation.
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Boris Pasche Research Topics

Disease

38Neoplasms (Cancer)
01/2021 - 01/2003
14Breast Neoplasms (Breast Cancer)
03/2021 - 09/2003
13Colorectal Neoplasms (Colorectal Cancer)
01/2014 - 04/2002
10Neoplasm Metastasis (Metastasis)
03/2021 - 10/2005
5Fibrosis (Cirrhosis)
01/2016 - 11/2007
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 06/2004
4Adenocarcinoma
12/2018 - 01/2009
4Colonic Neoplasms (Colon Cancer)
01/2017 - 02/2004
4Lung Neoplasms (Lung Cancer)
01/2017 - 06/2004
3Brain Neoplasms (Brain Tumor)
06/2019 - 01/2018
3Carcinogenesis
01/2017 - 12/2007
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 12/2009
2Obesity
09/2011 - 10/2008
2Prostatic Neoplasms (Prostate Cancer)
09/2011 - 09/2004
2Systemic Scleroderma (Systemic Sclerosis)
04/2009 - 11/2008
2Hyperplasia
04/2009 - 11/2008
2Ovarian Neoplasms (Ovarian Cancer)
09/2004 - 09/2003
1Pathologic Complete Response
01/2021
1Body Weight (Weight, Body)
01/2021
1Esophageal Neoplasms (Esophageal Cancer)
01/2021
1Weight Loss (Weight Reduction)
01/2021
1Adenocarcinoma of Lung
01/2021
1Glioma (Gliomas)
01/2020
1Disease Progression
06/2019
1Stomach Neoplasms (Stomach Cancer)
12/2018
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2018
1Necrosis
01/2017
1Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)
07/2016
1Cardiovascular Diseases (Cardiovascular Disease)
06/2014
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2012
1Insulin Resistance
09/2011
1Fatigue
04/2009
1Autoimmune Diseases (Autoimmune Disease)
11/2008
1Hyperinsulinism (Hyperinsulinemia)
10/2008

Drug/Important Bio-Agent (IBA)

20Transforming Growth Factor-beta Type I ReceptorIBA
01/2014 - 09/2003
18Transforming Growth Factor beta (TGF-beta)IBA
02/2014 - 01/2003
5Biomarkers (Surrogate Marker)IBA
01/2020 - 04/2002
4RNA (Ribonucleic Acid)IBA
01/2020 - 05/2010
4AdiponectinIBA
09/2011 - 05/2008
4Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
09/2009 - 09/2004
3LigandsIBA
12/2018 - 08/2004
3Adiponectin ReceptorsIBA
09/2011 - 05/2008
3Proteins (Proteins, Gene)FDA Link
09/2011 - 06/2004
2Transcription Factors (Transcription Factor)IBA
03/2021 - 01/2020
2Fluorouracil (Carac)FDA LinkGeneric
01/2021 - 01/2017
2Interleukin-8 (Interleukin 8)IBA
01/2017 - 01/2016
2Transforming Growth Factor-beta Type II ReceptorIBA
01/2017 - 01/2010
2DNA (Deoxyribonucleic Acid)IBA
01/2017 - 05/2010
2Antineoplastic Agents (Antineoplastics)IBA
01/2017 - 06/2014
2EnzymesIBA
01/2017 - 06/2010
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
06/2014 - 06/2013
2Interleukin-6 (Interleukin 6)IBA
02/2013 - 04/2012
2Hormones (Hormone)IBA
04/2009 - 10/2008
2Biological ProductsIBA
04/2009 - 03/2008
1Cisplatin (Platino)FDA LinkGeneric
01/2021
1Carboplatin (JM8)FDA LinkGeneric
01/2021
1Paclitaxel (Taxol)FDA LinkGeneric
01/2021
1SolutionsIBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA
10/2020
1AMP-Activated Protein KinasesIBA
10/2020
1Antisense OligonucleotidesIBA
01/2020
1p38 Mitogen-Activated Protein KinasesIBA
06/2019
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
06/2019
1CateninsIBA
06/2019
1Calcium Channels (Calcium Channel)IBA
06/2019
1Cystatin AIBA
03/2019
1Small Cytoplasmic RNAIBA
01/2019
1AntigensIBA
12/2018
1AntibodiesIBA
01/2018
1Irinotecan (Camptosar)FDA LinkGeneric
01/2017
1Pharmaceutical PreparationsIBA
01/2017
1Lysine (L-Lysine)FDA Link
01/2017
1MethyltransferasesIBA
01/2017
1Leucovorin (Folinic Acid)FDA Link
01/2017
1devimistatIBA
01/2017
1folfirinoxIBA
01/2017
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2017
1pterostilbeneIBA
01/2016
1Granzymes (Granzyme)IBA
01/2016
1LuciferasesIBA
02/2013
1CytokinesIBA
04/2012
1ORALIT (ORS)IBA
04/2012
1Transforming Growth Factors (Transforming Growth Factor)IBA
05/2009
1Therapeutic UsesIBA
04/2009
1Cyclin D1IBA
01/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2008
1Messenger RNA (mRNA)IBA
05/2008
1Aligeron (AS 2)IBA
12/2007

Therapy/Procedure

6Therapeutics
06/2019 - 04/2002
4Drug Therapy (Chemotherapy)
01/2021 - 06/2004
2Craniotomy
01/2020 - 10/2019
2Radiotherapy
06/2019 - 01/2017
2Precision Medicine
07/2016 - 05/2014
2Psychology Biofeedback (Biofeedback)
11/2013 - 04/2009
1Chemoradiotherapy
01/2021
1Immunotherapy
01/2021
1Secondary Prevention
06/2014
1Hematopoietic Stem Cell Transplantation
10/2012
1Aftercare (After-Treatment)
04/2009